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We Provide Comprehensive Service Solutions In RNA Therapeutics

mRNA vaccines
An mRNA vaccine is a type of vaccine that uses genetic instructions in the form of messenger RNA to teach cells how to produce a specific protein that triggers an immune response, helping to protect against specific diseases. Our cutting-edge capabilities harness messenger RNA technology to efficiently manufacture and deliver high-quality mRNA vaccines
Synthetic RNAs
Our state-of-the-art capabilities enable the efficient production and delivery of high-quality synthetic RNA, paving the way for innovative applications in gene therapy, research, and therapeutic development
Antisense RNAs
Antisense RNAs are a class of RNA molecules that are complementary in sequence to specific target messenger RNAs (mRNAs) within cells. These antisense RNAs can bind to their target mRNAs, forming a double-stranded RNA complex, which can inhibit or regulate the expression of the target gene.
RNA Interference
RNA interference (RNAi) is a biological process that regulates gene expression by silencing specific genes through the action of small RNA molecules. In RNA interference, short double-stranded RNA molecules, known as small interfering RNAs (siRNAs), or short hairpin RNAs (shRNAs), are introduced into cells
CRSPR/Cas9
CRISPR/Cas9 is a revolutionary gene-editing technology that uses a guide RNA to direct the Cas9 enzyme to specific DNA sequences, enabling precise modifications. It has diverse applications in research, medicine, and agriculture, offering tremendous potential for targeted genetic modifications and advancements in various fields
mRNA Synthesis
Our services include mRNA synthesis, purification, quality control, and formulation. We use state-of-the-art equipment and techniques to ensure the highest quality and purity of our mRNA molecules. Our mRNA synthesis process is designed to minimize the risk of contamination and ensure consistent results

Our Transcription Service Includes

Construct design and codon optimization

Construct design involves the strategic arrangement of DNA or RNA sequences to achieve desired functionalities, such as gene expression or protein production. Codon optimization, on the other hand, focuses on selecting the optimal codons within a gene sequence to enhance protein expression levels in specific host organisms, considering factors like codon usage bias and mRNA stability.

DNA Syntehsis

Oligo synthesis involves the chemical production of short DNA or RNA fragments, typically used as primers or probes in molecular biology experiments. Gene synthesis, on the other hand, is the process of creating longer DNA sequences, including entire genes, through chemical assembly. Gene synthesis enables the design and construction of custom DNA sequences for applications in synthetic biology, genetic engineering, and biotechnology

Plasmid Prep

Unlock the potential of genetic engineering with our comprehensive Cloning and Plasmid Prep services. Our expert team specializes in efficient DNA fragment insertion into versatile plasmid vectors, enabling the generation of multiple copies of desired DNA sequences. With our streamlined plasmid prep process, we provide high-quality, purified DNA samples, empowering researchers with the tools they need for successful downstream applications and genetic manipulation

IVT and QC

Experience reliable In Vitro Transcription (IVT) and Quality Control (QC) services with our cutting-edge molecular biology solutions. Our expert team utilizes advanced techniques to produce high-quality RNA transcripts for a wide range of applications, including RNA-based research, gene expression analysis, and therapeutic development. With rigorous QC measures, we ensure the integrity and accuracy of your RNA samples, delivering reliable results that meet the highest standards of quality and precision

LNPs and Targeted Delivery
We specializing in the design, development, and manufacture of custom lipid nanoparticle (LNP) formulations for the delivery of a wide range of nucleic acid-based therapeutics, including mRNA, siRNA, and CRISPR/Cas9 gene editing tools.
LNP synthesis and optimization
We can synthesize LNPs using a variety of lipid components and optimize the formulation for optimal delivery efficiency and safety
RNA encapsulation
We can encapsulate a wide range of RNA-based therapeutics, including mRNA, siRNA, and miRNA, in our custom LNP formulations
CRISPR/Cas9 delivery
We can design and optimize LNP formulations for the delivery of CRISPR/Cas9 gene editing tools, including sgRNA and Cas9 protein
Analytical characterization
We use dynamic light scattering, zeta potential measurement, and transmission electron microscopy, to study our LNP formulations

RNA Encapsulation

Our mRNA design platform offers mRNA with high stability and translation, and peace of mind to you. Let our expert scientists help you design the mRNA candidates for your researchWe have extensive experience in the encapsulation of a wide range of RNA-based therapeutics, including mRNA, siRNA, and miRNA, in our custom LNP formulations. Our RNA encapsulation services can help you achieve improved delivery efficiency and targeting of your RNA therapeutics to specific tissues and cells. We use state-of-the-art techniques to optimize RNA encapsulation efficiency, including electroporation and microfluidic mixing. Our team of experts can work with you to select the optimal LNP formulation for your specific RNA therapeutic and to ensure its stability and activity during encapsulation.

CRISPR/Cas9 Delivery

We specialize in the development of LNP formulations for the delivery of CRISPR/Cas9 gene editing tools, including sgRNA and Cas9 protein. Our CRISPR/Cas9 delivery services can help you achieve efficient and specific gene editing in a wide range of cell types and tissues. We use advanced techniques to optimize the delivery efficiency of CRISPR/Cas9 tools, including the use of endosomal escape enhancers and the incorporation of targeting ligands. Our team of experts can work with you to design and optimize a custom LNP formulation for your specific CRISPR/Cas9 therapeutic application

Analytical Characterization
We use a range of analytical techniques to characterize the physical properties of our LNP formulations and ensure their quality and consistency. Our analytical characterization services include dynamic light scattering, zeta potential measurement, and transmission electron microscopy. We use these techniques to monitor the particle size, size distribution, and surface charge of our LNPs and to ensure their stability and activity during encapsulation. Our goal is to provide you with the highest quality LNP formulations possible, with consistent properties and performance across multiple batches
Particle size analysis
We use dynamic light scattering to determine the size and size distribution of our LNPs. This information is crucial for ensuring optimal delivery efficiency and minimizing off-target effects
Zeta potential measurement
We measure the zeta potential of our LNPs to determine their surface charge, which is an important factor in their stability and their interaction with cells and tissues
Transmission electron microscopy
We use transmission electron microscopy to visualize the morphology of our LNPs and to ensure their uniformity and consistency
Stability testing
This includes testing for physical stability, such as particle size and zeta potential changes, as well as biological activity, such as the delivery efficiency and gene silencing capability of the encapsulated RNA

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